Extreme Wrinkle Defense

Trienelle’s Extreme Wrinkle Defense is a professional strength wrinkle-smoothing serum designed to relax and diminish the appearance of wrinkles, expression lines and fine lines- starting in just 7 days!

The “Youth Molecule” Argireline relaxes facial muscles to help reverse the appearance of existing wrinkles for tighter, smoother, younger-looking skin. Matrixyl 3000, the “Revitalizer,” revives your youthful skin, improving the elasticity. It fortifies and improves the appearance of skin for a firm, youthful glow. The Mega-moisturizer, Hyaluronic Acid, delivers supple, smooth skin and a silky texture.

This lightweight, velvety smooth serum is the perfect addition to your current skincare regimen. It has been formulated to be easily applied to skin under your current moisturizer, or as the perfect base for makeup.

Try it today and watch your deepest wrinkles vanish, starting in just 7 days… Guaranteed.

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Buy 1 Bottles$85.00
Buy 3 Bottles$255.00 FREE Shipping
Buy 6 Bottles$510.00 FREE Shipping

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  • Helps reduce the appearance of expression wrinkles starting in just 7 days!
  • Reverses existing wrinkles for tighter, younger looking skin
  • Improves the tone and texture of skin
  • Visibly plumps, firms and lifts
  • Helps relax facial muscles to reduce the appearance of wrinkles in the future
  • Hydrates and replenishes
  • Perfect for all skin types, even sensitive skin
  • Easily added to your current skincare regimen
  • Light, silky serum
  • Fragrance-free
  • Bottle size- 30 ml/1 fl ounce

Helpful tips:

  • Please note: The serum is very light (you might even call it “watery”)… but that’s exactly how it’s supposed to be! This allows it to absorb into your skin quickly and start working right away. Plus, it also means…
  • You can add it into your normal beauty routine. Because it’s a serum, it will work best if you use it twice a day, immediately after cleansing and before moisturizing. Or feel free to use it entirely on its own! To dispense the product…
  • We recommend tipping the bottle slightly over your fingertips, or the palm of your hand, and pressing the pump slowly to dispense the serum. You’ll only need to use a thin layer, but feel free to apply more to any area you’d especially like to target… your face, neck, or décolletage too! (For most women, this will be ½ to one full pump.)


Apply to freshly cleansed skin morning and evening, paying particular attention to wrinkles and expression lines. For best results, follow with Daily Renewal Creme in the morning, and Nightly Restoration Creme in the evening.

Dramatic results:

All thanks to the triple-pronged approach that targets every sign of aging:

  • Beauty Agent #1 to Reverse Your Wrinkles. This is an ultra-high peptide concentration that works wonders to smooth your skin and reverse the look of crow’s feet, laugh lines, deep frown lines… and everything in between. Even your very worst wrinkles have finally met their match!
  • Beauty Agent #2 to Fortify Your Skin. A potent dose of this powerhouse goes to work right away targeting the thickness and fullness in your skin to revive its youthful appearance. Look forward to rewinding the clock for firmer-looking, “airbrushed” skin…
  • And the incredible Beauty Agent BONUS to Reveal Your Glow. A healthy moisturizing shot delivers supple, smooth looking skin, and a silky texture to parched skin… it even provides that “dewy” glow that’s so sought-after, but can be so hard to actually achieve.

Extreme Wrinkle Defense just wouldn’t be a complete solution without clinically proven amounts of all three ingredients. And best of all… this entire skin-beautifying formula is packed into a light, silky serum. (What’s not to love!?)

We know you’ll be absolutely floored with your results when you see this serum’s power in action, but if you’re ever less than thrilled—just say the word.

You’re completely covered by our full 365-day money-back guarantee.

There’s no risk to you and a lifetime of gorgeous, glowing, young skin awaits.

So what are you waiting for? You’re just 7 days away from a more youthful, radiant You. Click “Add to Cart” and order now!

Avoid contact with eyes. If product gets into your eyes, rinse thoroughly with water. Contact a physician if irrigation is not successful or you have an adverse reaction to the product. Keep out of Reach of Children

My lines have relaxed and are less noticeable! Even my forehead and around my mouth looks younger and smoother. My sister even noticed that my face is looking younger – even out in the sunlight – and has asked for some of whatever I’m using.

— Sandra H. from Middletown, NY

Now that I look at the pictures side-by-side, I really do think the serum made a difference! I averaged using the serum 1x per day, but If I had used it twice a day imagine what baby-butt-smooth skin I might have right now!!!!!!! 
— Sarah P. from Orlando, FL